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Yes, you absolutely can! You will have to us the EthereumJS-tx package from NPM, you can get more information here: It's as simple as: const EthereumTx = require('ethereumjs-tx').Transaction const privateKey = Buffer.from( 'e331b6d69882b4cb4ea581d88e0b604039a3de5967688d3dcffdd2270c0fd109', 'hex', ) const ...

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