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Javascript API and library for Ethereum To develop applications on Ethereum, you can use the web3 object provided by the web3.js library. Under the hood it communicates to a local node through RPC calls. web3.js works with any Ethereum node, which exposes an RPC layer. https://github.com/ethereum/wiki/wiki/JavaScript-API

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Sign and send transaction (call contract function)

With ethers.js v5: create your smart contract instance const instance = new Contract(address, abi, signerOrProvider) or just the interface const interface = new ethers.utils.Interface(abi) encode …
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