There are several different types of master's degrees that I am aware of. There are
- project-based degrees (e.g., at Vrije Universiteit Amsterdam);
- course-based degrees (e.g., at Stanford University); and
- research-based degrees.
Some places offer more than one type and many don't have a pure research- or course-based degree but, instead, offer a blend. Getting any one of these may improve your employability in the blockchain space, but given the newness of the field, I don't know how many jobs would require a master's or offer better pay for one.
Thus, any net financial benefit would come from any practical benefits you would obtain in terms of knowledge (which could help with your versatility or skillset) that you can leverage for promotions or building your own successful company. So... what sorts of benefits might you get for each of the above?
The rest of this answer is purely opinion-based.
I personally don't see enrolling in and completing university courses as providing more value from a learning standpoint that could not be obtained in other ways (e.g., by reading or doing applied work), though your learning style may mean you prefer to have material delivered to you by a person. Then I would assume you would want to select your place of study on the people teaching the courses and thus your question is too broad to be of use to your specific case.
From my conversations with people from around the world that have are working on project-based master's, they seem to work largely independently of their supervisors. They may receive mentorship but I think the bulk of the benefit is derived from working with peers who are working on the same larger project or on similar projects. This sounds an awful lot like gaining the benefits of having a job. If you work for a small enough company (or start your own project), you might be able to work on aspects of a large project that interest you and provides you with versatility. Otherwise, if you're focusing on a specific aspect of blockchain at a company, you can gain depth, if that's your desire.
If you want to do research, I think a university is a good place to do so: you have a lot of academic freedom since you can find a place that is doing the sort of research you're interested in and select a supervisor with whom you would like to work. You'll probably get to go to conferences (though my sample population for determining "probably" is very biased); conferences allow for a lot of idea cross-pollination and a chance meet other people in the field. The research itself from many (but not all) computer science conferences is available for free on-line.
What constitutes a "Master's degree" varies greatly, but from an employment standpoint, a master's degree is probably irrelevant at this time. The only type of blockchain-related master's potentially worth pursuing at this time, IMHO, is a research-based master's.
Disclosure: I have a course- and research-based master's degree, but not related to blockchain.